The interoperability of the entire production chain of clear aligners is essential to a high-performing, consistent and validated workflow. Vincent Icart from Prodways and Sune Nørregaard from 3Shape take a deep dive into the hardware and software components of a successful production chain, from the intraoral scanner and processing software to the cleaning and curing system. They also discuss the process of developing treatment plans with micrometric precision that transform into a production plan to serve as a guide for the additive manufacturing machine or 3D printer.