Rapid improvements in CAD/CAM materials have created a growing demand for monolithic restorations. With roughly 85% of all metal-free restorations now monolithic, technicians must find new materials and techniques for achieving esthetic outcomes traditionally only possible with ceramic layering. Don Cornell looks critically at CAD/CAM materials, where we are today and where we are headed, and how to achieve exceptional esthetic outcomes with monolithic and minimally layered restorations.