The popularity of monolithic zirconia and single-phase all-ceramic materials dominate the restorative market and are increasingly the treatment choice for simple and complex restorative solutions. Ken Malament, DDS, MScD, explores how these materials have transformed the predictable esthetics and long-term clinical survival rate of all-ceramic restorations and presents original research on the clinical behavior of these materials, including more than 3,800 IPS e.max lithium disilicate restorations.